Molecular Biology – Part 3: RNA Processing and Translation

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Обучение бесплатное
Certificate
Сертификация платная
Duration
10 месяцев
О курсе

In Part 3 of 7.28x, you’ll explore translation of mRNA to protein, a key part of the central dogma of biology. Do you know how RNA turnover or RNA splicing affects the outcome of translation? Although not official steps in the central dogma, the mechanisms of RNA processing strongly influence gene expression.

Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?

Take a behind-the-scenes look at modern molecular biology, from the classic experimental events that identified the proteins and elements involved in translation and RNA splicing to cutting-edge assays that apply the power of genome sequencing. Do you feel confident in your ability to design molecular biology experiments and interpret data from them? We've designed the assessments in this course to build your experimental design and data analysis skills.

Let’s explore the limits of our current knowledge about the translation machinery and mechanisms of RNA turnover and splicing. If you are up for the challenge, join us in 7.28.3x Molecular Biology: RNA Processing and Translation.

Программа
Molecular Biology – Part 3: RNA Processing and Translation
An in-depth adventure through RNA Processing and Translation. Strengthen your scientific thinking and biological experimental design skills.
Что Вы изучите?
  • How to compare and contrast translation in bacteria and eukaryotes
  • How to describe several mechanisms of RNA turnover and RNA splicing
  • How to analyze protein structures to infer functional information
  • How to design the best experiment to test a hypothesis
  • How to interpret data from translation and RNA processing experiments
Лекторы
Stephen P. Bell
Stephen P. Bell
HHMI Investigator; Professor of Biology MIT
Steve Bell is a Professor of Biology in the Department of Biology at MIT and an HHMI Investigator. Steve and his lab study the regulation of eukaryotic replication using biochemical, genetic, and molecular biology approaches. He has received the institute-wide Everett Moore Baker Memorial Teaching Award as well as a School of Science Teaching Prize for Excellence in Undergraduate Education. Along with Tania, Steve co-authored a popular molecular biology textbook with James Watson.
Tania A. Baker
Tania A. Baker
HHMI Investigator; Whitehead Professor of Biology MIT
Tania Baker is an E. C. Whitehead Professor of Biology and an HHMI Investigator. Tania recently received the Arthur Kornberg and Paul Berg Lifetime Achievement Award for her research in replication and AAA+ unfoldases, which remove potentially toxic proteins. Tania has also been recognized for her commitment to teaching as a recipient of the Margaret MacVicar Faculty Fellowship and a School of Science Teaching Prize for Excellence in Undergraduate Education. In addition to authoring the textbook with Steve, as a graduate student, Tania co-authored a well-known textbook on DNA replication with Arthur Kornberg.
Mary Ellen Wiltrout
Mary Ellen Wiltrout
MITx Digital Learning Scientist, Department of Biology Massachusetts Institute of Technology
Dr. Mary Ellen Wiltrout is an MITx Digital Learning Scientist in the Department of Biology at MIT. She previously completed her Ph.D. in Graham Walker’s lab from the Department of Biology at MIT, taught molecular biology at Harvard University, and returned to MIT as a core development member of MITx 7.00x. She now oversees and manages all of the MITx projects for the Department of Biology at MIT.
Sera Thornton
Sera Thornton
MITx Digital Learning Fellow, Department of Biology Massachusetts Institute of Technology
Dr. Sera Thornton was an MITx Digital Learning Fellow in the Department of Biology at MIT from 2014 to 2017. In conjunction with her role as a core member of the MITx Biology course development team, Sera curated and created many of the graphics for MITx Biology courses, including animating the lecture video inserts for MITx 7.28x. She previously completed her Ph.D. studying epigenetic gene regulation in stem cell lineage commitment and differentiation in the Boyer lab at MIT.
Swati Carr
Swati Carr
MITx Digital Learning Fellow, Department of Biology MIT
Dr. Swati Carr is a Digital Learning Lab Fellow in the Department of Biology at MIT. As part of her role as a core member of the MITx Biology course development team, Swati develops and tests assessments for their courses. She completed her Ph.D. by developing methodology for improving the predictability of engineered genetic device behavior in the Densmore lab at Boston University.
Платформа
EdX
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